Calcitonin's effect on blood calcium levels?

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Multiple Choice

Calcitonin's effect on blood calcium levels?

Explanation:
Calcitonin lowers blood calcium levels by inhibiting osteoclast-mediated bone resorption, which reduces calcium release from bone into the bloodstream. It is produced by the thyroid's parafollicular C cells in response to high serum calcium. In addition, it can modestly increase calcium excretion by the kidneys, reinforcing the decrease in serum calcium. Although PTH and vitamin D are the major regulators, calcitonin’s net effect when calcium is high is to decrease blood calcium, not increase or leave it unchanged.

Calcitonin lowers blood calcium levels by inhibiting osteoclast-mediated bone resorption, which reduces calcium release from bone into the bloodstream. It is produced by the thyroid's parafollicular C cells in response to high serum calcium. In addition, it can modestly increase calcium excretion by the kidneys, reinforcing the decrease in serum calcium. Although PTH and vitamin D are the major regulators, calcitonin’s net effect when calcium is high is to decrease blood calcium, not increase or leave it unchanged.

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