Gigantism and Acromegaly are both caused by excess Growth Hormone.

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Multiple Choice

Gigantism and Acromegaly are both caused by excess Growth Hormone.

Explanation:
Excess growth hormone drives overgrowth of size and tissues. In children, growth plates are still open, so too much GH pushes linear bone growth and results in gigantism with tall stature. In adults, the bones can no longer lengthen, but GH still stimulates soft tissue and organ growth, producing acromegaly with enlarged hands, feet, facial features, and organomegaly. Both conditions stem from too much GH, most commonly from a GH-secreting pituitary adenoma. The key difference is timing: before epiphyseal closure leads to gigantism, after closure leads to acromegaly.

Excess growth hormone drives overgrowth of size and tissues. In children, growth plates are still open, so too much GH pushes linear bone growth and results in gigantism with tall stature. In adults, the bones can no longer lengthen, but GH still stimulates soft tissue and organ growth, producing acromegaly with enlarged hands, feet, facial features, and organomegaly. Both conditions stem from too much GH, most commonly from a GH-secreting pituitary adenoma. The key difference is timing: before epiphyseal closure leads to gigantism, after closure leads to acromegaly.

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