Intrinsic factor is produced by which gastric cell type?

Enhance your NBEO Histology Test preparation skills with our quiz. Dive into multiple choice questions explained with hints and detailed answers. Ace your NBEO exam with confidence!

Multiple Choice

Intrinsic factor is produced by which gastric cell type?

Explanation:
Intrinsic factor is produced by parietal cells in the stomach. These cells, also known as oxyntic cells, are responsible for secreting both hydrochloric acid and intrinsic factor. Intrinsic factor is a glycoprotein essential for the intestinal absorption of vitamin B12; it binds B12 in the stomach and forms a complex that is taken up in the terminal ileum. Without intrinsic factor, vitamin B12 cannot be efficiently absorbed, leading to pernicious anemia if deficiency persists. Chief cells release pepsinogen, G cells release gastrin, and mucous cells secrete protective mucus; none of these produce intrinsic factor.

Intrinsic factor is produced by parietal cells in the stomach. These cells, also known as oxyntic cells, are responsible for secreting both hydrochloric acid and intrinsic factor. Intrinsic factor is a glycoprotein essential for the intestinal absorption of vitamin B12; it binds B12 in the stomach and forms a complex that is taken up in the terminal ileum. Without intrinsic factor, vitamin B12 cannot be efficiently absorbed, leading to pernicious anemia if deficiency persists. Chief cells release pepsinogen, G cells release gastrin, and mucous cells secrete protective mucus; none of these produce intrinsic factor.

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